A short video from Alfresco's partner Zia Consulting demonstrating how IMAP integration works in Alfresco. You can access and iteract the whole document repository from a regular email client, like Outlook, Thunderbird or Apple Mail. This opens a set of possible interesting use cases within a company, and doesn't force some employees to learn a new tool to effectively use the document management system.
Some more links about email management with Alfresco: